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[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Chen Y., Xiao M., Zhao L., Huang Y., Lin Y., Xie T., Tian J., Wang Q., Tang Y., Su Z

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It was suggested that binding affinity of exendin-4 solely depends on its interaction with the NTD of GLP-1R, not with TM helices and ECLs because the binding affinity of exendin-4 did not alter when it bound to the isolated NTD of GLP-1R

Torin-1 is a potent inhibitor of both mTOR complexes 1 and 2, namely mTORC1 and mTORC2