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The FDA has issued cautions regarding dosing inconsistencies and unapproved GLP-1 compounded products

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Of those, 8% (44)[2] were issued for medical devices

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No head-to-head clinical trials have been conducted, so direct efficacy comparisons with approved therapies are not currently possible

Researchers at 5mg who experience significant end-of-week appetite return but tolerate the medication well otherwise are reasonable candidates for split dosing at this level