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As of February 2025, the FDA declared that the semaglutide shortage was resolved

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112,113 Furthermore, lifestyle factors may enhance metabolic risks, exacerbating the likelihood of biliary disease in susceptible individuals

FDA Drug Trial Snapshot: Ozempic Novo Nordisk Ozempic Product Page JAMA Effect of Subcutaneous Semaglutide on Weight Loss in Adults With Overweight or Obesity NEJM Once-Weekly Semaglutide in Adults with Overweight or Obesity American Diabetes Association Standards of Care in Diabetes2024 Medical Literacy Initiative Understanding Ozempic UC Davis Health Can weight loss medications really help you lose weight

Numerous factors could contribute to a decline in lean mass with weight loss, and many of the cited studies did not in fact measure muscle mass or distinguish it from other components of lean mass such as organs, bone, or body water