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Future research should focus on mechanistic studies, long-term safety, and identifying biomarkers to predict dermatologic responses, ultimately guiding personalized treatment approaches

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10.1016/j.bbamem.2012.07.032 87 SchelshornD.JolyF.MutelS.HampeC.BretonB.MutelV.et al (2012)

This is mainly driven by a high prevalence of type 2 diabetes and obesity in the region

In addition to insulin resistance and -cell dysfunction, impaired incretin effect in T2D plays a major role in the progression of -cell failure and hyperglycemia (26,27)