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Given the tremendous costs of treating cardiovascular disease and continuing renal replacement therapy, the suspected total benefits obtained from therapy should not be overlooked

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Kims analysis was done before the FDA approved GLP-1 drugs for chronic kidney disease, potentially sparing people from progressing to end-stage renal disease

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Taking too much phentermine over time can lead to chronic intoxication, which can cause trouble sleeping, irritability, personality changes, hyperactivity, psychosis (similar to schizophrenia), and severe skin problems

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Scott Gottlieb, the FDAs former commissioner, said on CNBC that many of the compounds wont deliver the expected benefit. The agencys safety concerns appear to be well founded: between February 2019 and December 2023, the FDA received 352 adverse event reports related to compounded GLP-1 drugs, including five deaths

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