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Insulin works by directly adding the hormone insulin to the body

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74 Brain Health Recent studies suggest GLP-1RA drugs reduce neuroinflammation and improve brain insulin sensitivity

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Oral semaglutide also resulted in a greater mean reduction in weight from baseline when compared with liraglutide and placebo (estimated mean change from baseline of -1.6 kg, -1.1 kg, and -0.3 kg, respectively [ P = .0006 for oral semaglutide vs

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In addition to compositional changes, GLP-1 appears to influence the inflammatory state of the gut

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Weight loss from weekly semaglutide injections accompanied significant reductions in pain related to knee osteoarthritis, according to data published in The New England Journal of Medicine

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