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Teichholz, L

Compounded semaglutide is not FDA-approved for weight loss or any other use

There was a one-month increase of 18.6% in first-time AOM prescribing between December 2024 (when first-time AOMs accounted for 0.34% of all prescriptions) and January 2025 (when first-time AOMs accounted for 0.41% of all prescriptions)

Weight loss depends on many factors including medical history, starting weight, nutrition, physical activity, medication adherence, and regular follow-up care

This may be partly mediated by improvements in weight loss and glucose control

Evidence proving that chronic sub-label dosing yields similar long-term outcomes is lacking