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20 :5-8 Key words: type 2 diabetes, cardiovascular outcome studies, SGLT2 inhibitors, GLP-1 receptor agonists, pioglitazone, REWIND, DAPA-HF, PIONEER 6 As we enter a new decade it is timely to reflect on the many advances in pharmacological therapies for type 2 diabetes that occurred with respect to cardiovascular protection during the last 5 years

When activated by SLU-PP-332, ERR increases mitochondrial biogenesis, enhances fat oxidation, and improves metabolic efficiencysimilar to endurance exercise training

These studies are helpful, but they cannot prove cause and effect
Immunol Res 54 , 7582 (2012)

They can adjust your dosage of insulin to reduce your risk of low blood sugar
Allow yourself about 90 seconds of rest between sets
