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Furthermore, cardiovascular results for oral semaglutide were similar to the results observed in the SUSTAIN-6 trial with injectable semaglutide, suggesting that the oral and SC formulations share similar cardiovascular safety profiles

Medical screening required

Existing CVOT subgroup analyses already provide a basis for this, consistently showing greater benefits in patients with established ASCVD compared to those in a primary prevention setting [51]

Several other conditions, including a history of pancreatitis, gallbladder disease, severe gastroparesis, severe kidney disease, diabetic retinopathy, and a history of an eating disorder, need extra clinical caution rather than being automatic exclusions