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The stock also vastly outperformed the US stock market: from the launch of Zepbound to the end of 2023, Lilly rose more than 75 per cent, compared to a rise of just over 50 per cent for the S&P 500 index over the same period

The primary difference is that retatrutide is a newer compound with less long-term stability data available, so following the conservative 28-day post-reconstitution window is especially important

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The fat-to-lean mass ratio In the SURMOUNT-1 body composition substudy, researchers used dual-energy X-ray absorptiometry, the gold standard for measuring body composition, to track exactly what was being lost

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