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Although it has been reported that the risk of EWDR is increased by faster or more effective lowering of HbA 1c in individuals treated with insulin or a sulfonylurea [14, 25], in our study reduction in HbA 1c was not independently associated with increased odds of the PDR endpoint

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Healthcare transformation should remain accessible rather than restricted to only wealthy populations
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A GTAA1c level of 4.5 predicted PR with 72.3% sensitivity and 92% specificity

Many patients find that side effects diminish significantly after the first few weeks

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