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About 6% and 9% of women on GLP-1 RAs with and without type 2 diabetes used long-acting reversible contraception methods, compared to 11% overall for Australian women

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Although there is limited direct evidence for this species having functional effects on host metabolic profile, studies in DIO mice have demonstrated reduced adiposity and improved glucose tolerance following oral administration of Akkermansia muciniphila 71,72

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Methods In a randomised, double-blind, three-period crossover study, 31 individuals with T2DM (1864 years, body weight 80120 kg, glycosylated haemoglobin 6.08.5%) received single subcutaneous injections of IcoSema (175 U icodec, 0.5 mg semaglutide), icodec (175 U) or semaglutide (0.5 mg) with 69 weeks washout