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Description
Mechanism: increased fatty acid oxidation plus increased basal metabolic rate
Metabolic mechanisms MOTS-c enhances insulin sensitivity through AMPK pathway activation, the master regulator of cellular energy homeostasis
It works by mimicking the effects of two hormones in the body: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)
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The medication slows gastric emptying, causing food to remain in the stomach longer and triggering gastrointestinal symptoms
Maintaining adequate hydration and electrolyte balance becomes especially important for patients on diuretics, as these medications already increase fluid and sodium loss
