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Introduced in the twenty-first century, glucagon-like peptide-1 receptor agonists (GLP-1RAs) are a class of antidiabetic drugs noted not only for their potent glucose-lowering effects but also for their cardiovascular and renal protective benefits

Learn what early research says about Orforglipron, a GLP-1 weight loss pill in trials

Though GLP-1 receptor agonists are effective for weight loss, they often come with side effects such as gas, nausea and constipation

Major drugmakers are investing in technologies to make GLP-1 pills more effective

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