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It has become the cornerstone of metabolic and obesity research owing to its potent insulin secretion, appetite suppression, and cardioprotective mechanisms
17 Additionally, activation of AMP-activated protein kinase (AMPK) by liraglutide leads to endothelial protection and angiogenesis regulated by the hypoxia inducible factor-1heme oxygenase-1 (Hif-1 HO-1) axis

FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014

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'These medicines are transforming obesity treatment and can achieve important weight loss

On the contrary, the following GLP-1 RAs were not associated with significant increased risk of GERD: liraglutide (RR 1.8614 [95% CI 0.6671, 5.1939
