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Both medications mimic GLP-1, but tirzepatide also targets another hormone that aids digestion called GIP
[3] Weight Loss: SURPASS-2 also reported significant weight loss for Mounjaro
The most frequently reported treatment-related adverse effects occurring with GLP-1 receptor agonists are gastrointestinal, primarily nausea (occurring in 2560% of patients in clinical trials), vomiting (515%), and diarrhea (1020%) (47)
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