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Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4

Approved 20 years ago as a treatment for diabetes, GLP-1 drugs have been found also to help patients significantly reduce weight

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As an Integrative and Functional Nutrition Health Coach, I want to provide a balanced discussion on this topic.

There is no confirmed elevated risk of suicidality, but surveillance remains warranted