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"When I treat patients in the diabetes clinic, I see a huge variation in response to these GLP-1-based medications and it is difficult to predict this response clinically," says endocrinologist Mahesh Umapathysivam, from Adelaide University in Australia

Increased Nausea: Both GLP-1 agonists and alcohol can irritate the stomach lining, leading to nausea

Animal studies have shown fetal growth concerns at high exposures

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Traumatic joint injury is another risk factor for the development of OA (post-traumatic osteoarthritis [PTOA]), associated with earlier disease onset than age-related OA and more readily affecting younger patients [6]