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headache (8% vs 7%)

The rapid renal clearance of many small peptides like GLP-1, together with its inactivation by DPP4, required development of longer-acting peptides with greater stability and enhanced resistance to DPP-4

Most recently, there are new indications for chronic kidney disease and sleep apnea

In addition to GLP-1, it also activates receptors of GIP, another hormone involved in regulating blood sugar and appetite

For a closer look at why doctors increasingly reach for these medicines in patients with heart or kidney risk, Part 8: GLP-1, Heart and Kidney Benefits is worth reading in full

However, I have noticed my cravings have gone down and my appetite is much smaller