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Results RCTs included in this study revealed that among 5800 patients, 78.22% (95% CI: 72.15% to 83.73%), 55.60% (95% CI: 46.54% to 64.47%), 32.28% (95% CI: 23.17% to 42.12%) achieved 5%, 10%, and 15% weight loss, respectively

Despite these observations, few studies have examined how these conditions and certain health factors like behaviors, hormone replacement therapy (HRT) or oral contraceptive use, hysterectomy or oophorectomy, infertility history, or the risk of both concurrent conditions may further contribute to the increased risk of premature mortality

However, in rare cases, there is an increased risk of thyroid cancer while taking liraglutide 2

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These strategies address both environmental factors and physiological adaptation to support comfort without compromising treatment efficacy

The main risk is indirect via gastrointestinal losses and low dietary intake