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Animal studies demonstrate that GLP-1 receptor agonists reduce dopamine signaling in this pathway

While these medications are available without a prescription, its still a good idea to consult your healthcare provider before using them alongside GLP-1 medications to ensure theyre safe and wont interact with your treatment

doi: 10.1038/s41571-025-01085-z

Over a 72 week period, patients can experience losing up to 1520% of their body weight

Ipsen filed a resubmission a few months later, which the FDA rejected in December 2022 and requested additional information regarding the data that the company had already provided

After the first month, the dose can increase to 0.5 mg