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While many people have found success from taking GLP-1s, this isnt the whole story

Most discontinuations were concentrated in weeks 112

JAMA Netw Open 3(10):e2020836 [DOI] [PMC free article] [PubMed] [Google Scholar] 64.Heymsfield SB, Coleman LA, Miller R, Rooks DS, Laurent D, Petricoul O et al (2021) Effect of bimagrumab vs placebo on body fat mass among adults with type 2 diabetes and obesity: A phase 2 randomized clinical trial

What it does is address the metabolic consequences of doing exactly what semaglutide is designed to do: create a sustained caloric deficit large enough to produce clinically meaningful weight reduction

"Even more troubling, many are turning to extreme, unproven methods without medical oversight, risking not just their health but their lives." As the slimmed-down trend has made its return over the past couple of years, the use of Ozempic and other injectable GLP-1 drugs for weight loss has soared

These drugs are marketed as harmless and easy