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2017;59:R110

The trial also met all key secondary endpoints, including improvements in waist circumference , systolic blood pressure, triglycerides, non-HDL cholesterol, LDL cholesterol, and serum uric acid

Most patients continue on weekly injections for several months to a year or longer, often seeing their greatest results during the first 3 to 6 months of treatment when combined with diet and lifestyle modifications under medical supervision

Consequently, the animals were surgically prepared in advance of the experiment to allow direct access to the lumen of the gut from the outside via an in-dwelling stoma

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Regular monitoring and provider communication remain essential for safety and efficacy