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Tirzepatide is not recommended during pregnancy

The slowing of digestion from Wegovy combined with the unabsorbed fat from Orlistat might increase the frequency and severity of GI symptoms, potentially leading to significant discomfort and impacting an individuals quality of life

Notably, more than one-third of participants achieved weight loss of 25% or greater, results previously seen only with bariatric surgery

The enforcement discretion periods for both semaglutide and tirzepatide expired in 2025

Hematologic cancers among patients with type 2 diabetes prescribed GLP-1 receptor agonists