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In the EU, Mounjaro (tirzepatide) is also approved for use alongside diet and exercise to help people lose weight or keep their weight under control

There is a potency to regain weight when taken off the drug

Patients are usually started on a lower dose and gradually titrated up to help reduce side effects

For example, a patient weighing 200 pounds could expect to lose 8 to 14 pounds in the first three months

Rats then received single tirzepatide or vehicle administration before alcohol reintroduction, with relapse-like drinking quantified as percentage change from baseline intake

Gallbladder problems including gallstones