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There is no direct dosage conversion between phentermine and semaglutide because they are fundamentally different drug classes
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Those drugs mimic this hormone in a more sustained way than your body can on its own, since natural GLP-1 only sticks around in your bloodstream for a couple of minutes

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Diabetologia 65 (8), 12511261

The presence of glucose in the blood triggers the release of the hormone insulin from the pancreas
