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However, because federal law does not require state-licensed pharmacies that are not outsourcing facilities to submit adverse events to FDA, many cases are likely going undocumented.FDA has also warned companies that have illegally sold unapproved drugs containing semaglutide, tirzepatide or retatrutide that are falsely labeled for research purposes or not for human consumption. These products have been sold directly to consumers for human use with dosing instructions

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This was a retrospective cohort study of adult patients with a body mass index (BMI)30kg/m2 prescribed GLP-1 analogue therapy at an obesity specialist clinic in Vancouver, Canada