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Addition: Introduce a prebiotic fiber (acacia or PHGG) at minimum dose

[ ] #DCATWeek #DCAT2026 #PharmaStrategy #GLP1 #TheMedicineMaker #BiotechNYC #SupplyChain To view or add a comment, sign in GLP-1 drugs are driving a seismic shift in how Americans eat

227 The probiotics Bifidobacterium BGN4 and Lactobacillus fermentum HFY06 can also mediate the differentiation of T cells, inhibit the expression of IL-1 and COX2, promote the expression of the anti-inflammatory cytokine IL-10, enhance epithelial barrier function and reduce damage to the intestinal barrier by inhibiting the NF-B signaling pathway

The broad use of GLP-1 agonists in children remains a concern to me, as the general public is unaware that in the majority of users, it will be a drug for life

However, probiotics are generally recognised as safe for most individuals, and their use for symptomatic gastrointestinal relief is supported by a broader evidence base in functional gastrointestinal disorders

For someone starting at 220 pounds, that difference represents approximately 7 additional pounds of weight loss with Retatrutide compared to Mounjaro