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Excessive incretin hormones may also contribute to pancreatic islet cell hyperplasia, leading to hyperinsulinism

Once released, it does several things at once: it prompts your pancreas to release insulin proportional to your current glucose level, signals your brain that you're full, slows the rate at which food leaves your stomach, and suppresses glucagon - the hormone that would otherwise push glucose higher between meals

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The roles of peripheral 5-HT are diverse, but it primarily regulates gut motility and plays a role in hemodynamics and vasoconstriction [20]

The optimal threshold BBPS is 6 in total or 2 per colonic segment