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Avoid weight/obesity bias in deciding who should discontinue GLP-1RA therapy
148 Hence, IR promotes the pathology of AD by reducing amyloid clearance and increasing tau hyperphosphorylation neurofibrillary tangles, 149 both of which are associated with cognitive impairment

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GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management

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doi: 10.3390/ijms23073587, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 5