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Our results are consistent with a post hoc analysis of the EXCEL trial [29] which concluded that exenatide combined with SGLT-2i reduced the risk of MACE (defined as cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) compared with exenatide monotherapy and also improved eGFR significantly

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Asian Pac J Trop Med (2017) 10:10306

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The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively