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Rybelsus Rybelsus made history in 2019 as the first oral GLP-1 receptor agonist to receive FDA approval

Frequency Once weekly, subcutaneous

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Glucagon: Associated with increased energy expenditure and metabolic regulation, including the breakdown of stored energy

Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist that works through similar mechanisms
