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A 2025 study published in JAMA Network Open found that most patients with obesity discontinue GLP-1 therapy within a year, particularly those without type 2 diabetes 1

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Glucagon-like peptide-1 receptor agonists and risk of parkinsons disease in patients with type 2 diabetes: a population-based cohort study

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Their diverse biological effects, coupled with a growing body of preclinical and clinical evidence, support the potential for GLP-1R agonists to be integrated into multidisciplinary pain management protocols