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We report that PPGNTS neurons encode satiation in mice, consistent with vagal gastrointestinal distension signalling
95% CI: -8.8, -2.0
From the approval of Orlistat (Xenical) in 1999, which focused on reducing dietary fat absorption, to the emergence of highly effective incretin-based therapies such as liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound), we have witnessed a fundamental shift in how obesity is understood and treated
Peter Attia, Andrew Huberman discusses GLP-1, specifically mentioning its role in weight management and its effects
June 2, 2026
