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A randomised controlled trial published in 2022 examined exenatide in individuals with AUD, finding no significant overall difference in alcohol consumption compared to placebo over a 26-week period, though a predefined subgroup analysis showed potential benefit specifically in participants with obesity

The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes

Plus, excessive weight loss of any kind while breastfeeding can impact your milk supply and make it hard to feed your baby

Older adults Older patients generally tolerate Wegovy well, but dose escalations may be personalised if side effects appear more pronounced

That gap matters because approval does not equal availability, and availability does not equal equitable patient access

For context, real-world data on oral semaglutide from Rybelsus doses up to 14 mg showed more modest results, around 5.7% weight reduction