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Nevertheless, there is little concordance between the available localization data from immunohistochemistry vs

These medications treat type 2 diabetes, obesity, and cardiometabolic risk

Accordingly, the bulk of the clinical evidence of the effects of the drug class on HF have been collected in the placebo-controlled CVOTs in people with type 2 diabetes and established CVD or CVD risk (Table 1) (Pfeffer et al., 2015
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doi: 10.1210/jc.2009-1062
J Clin Invest 91: 301307
