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The race to develop effective oral GLP-1 medications for obesity is heating up, and AstraZeneca is officially making its move

MG treatment induced apoptosis of beta cells, impaired mitochondrial function, and prolonged activation of AMP-dependent protein kinase (AMPK)

If GLP-1s do what the evidence suggests they will do, this will be one of the clearest demonstrations in modern psychiatry of why we fund preclinical research and why translational pipelines matter

Losing weight is challenging but achievable
