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For those who do not achieve glycemic targets with lifestyle therapy, metformin, and SGLT2i, or who cannot tolerate these agents, whether due to adverse events or because other restrictions apply, other medications are recommended

Additionally, over three times the number of people taking the drug achieved a 5% reduction, a generally accepted baseline for clinically meaningful weight loss

Wu J, Li T, Guo M et al (2024) Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue

The Role of Genetic Predisposition in GLP-1 Personalization Both Ro and Found rely on clinical assessment to select initial GLP-1 candidates, but neither platform currently offers genetic testing to predict response

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