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adults will qualify as obese by 2030 and nearly 25% as severely obese.i GLP-1s should be a key tool in managing obesity outcomes and costs: Despite higher prescription costs relative to nonusers, persistent GLP-1 use can decrease average annual total cost of care by $14K-$15K (14%) among chronically obese patients in the first one to two years of use

If you see particles, cloudiness, or discoloration, do not use the vial

Never inject into muscle tissue, as GLP-1 agonists are specifically formulated for subcutaneous administration
Because doses are so small, changes occur but

Rising costs lead insurers to drop weight loss drug coverage, further increasing patient burden, American Journal of Managed Care (2024) FDA approves first generic of once-daily GLP-1 injection to lower blood sugar in patients with type 2 diabetes, Food & Drug Administration (2024) What is medical necessity

Concerns have been expressed regarding the effects of these drugs on pancreatic and thyroid tissue, since animal studies and analyses of drug databases indicate an association of GLP-1 receptor agonists with pancreatitis, pancreatic cancer, and thyroid cancer
