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GLP-1 Receptor Agonists and Aspiration Risk: From Universal Holding to Risk-Based Perioperative Management Review Abstract Purpose The rapid adoption ofglucagon-like peptide-1 receptor agonists (GLP-1 RAs)anddual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 (GIP/GLP-1) receptor agonistshas transformed the management of type 2 diabetes mellitus and obesity

In a randomized controlled trial, 52 healthy obese individuals were, after a diet-induced 12% body weight loss, randomized to treatment with or without administration of the GLP-1RA liraglutide (1.2mg per day)

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Getting adequate protein intake prevents muscle loss and supports sustainable weight reduction during treatment