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Retatrutide may be the preferred option for patients with specific, co-existing metabolic issues, such as significant non-alcoholic fatty liver disease (MASH) , or for those who need to maximize weight loss results
Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)
Five rats per group that completed the full intervention protocol were included in obesity-related phenotyping analyses, accounting for unplanned discontinuations in some cohorts

The findings were published in The New England Journal of Medicine in April 2023

The safety population included adults who received at least 1 dose of the trial medication
