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Marketed under the brand name Mounjaro, tirzepatide represents a significant advancement in incretin-based therapies, offering dual agonist activity that distinguishes it from single GLP-1 receptor agonists such as semaglutide or liraglutide

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Scientists think the agonizing of both GIP and GLP-1 receptors is what causes drugs like tirzepatide to be more effective than those that only utilize GLP-1

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For persistent or severe symptoms, healthcare providers may consider temporarily interrupting treatment or reducing to a previously tolerated dose

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