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Effects of empagliflozin on risk for cardiovascular death and heart failure hospitalization across the spectrum of heart failure risk in the EMPA-REG OUTCOME trial

Wegovy commonly causes nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, especially when starting treatment or increasing doses

Now, if this precise entry mechanism/signalling phenomenon is halted, you get diabetes mellitus

Sabioni P, Le Foll B

This indicates that DPP4 plays a vital role in the extracellular protein metabolism of the kidney, particularly in the breakdown and hydrolysis of proline-containing peptides