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However, these benefits must be balanced against possible side effects of fluid retention and congestive HF [196, 197, 202], weight gain [196,197,198, 202, 203] and bone fracture [204, 205]
Retatrutide reconstitution involves mixing lyophilized (freeze-dried) powder with a sterile diluent to create an injectable solution

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Clinical recommendations to manage gastrointestinal adverse events in patients treated with Glp1 receptor agonists: a multidisciplinary expert consensus

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Some research has even found that using BMI to determine treatment may end up excluding a significant number of adults who have weight-related health conditions, such as metabolic syndrome
