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The orforglipron 45 mg oral daily dose conferred weight change from baseline of 12.6% at 26 weeks and 14.7% at 36 weeks
doi: 10.1111/dom.14054
Similarly, tirzepatide (Zepbound) demonstrated up to 22.5% weight loss in a 72-week trial with the same approach
For the gaming side, variety and fairness matter
doi: 10.1111/j.1463-1326.2011.01357.x
