semaglutide alzheimer's phase 3 ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of disease via the GLP-1R/SIRT1/GLUT4 pathway Weight Loss Drug Semaglutide Shows

Veterans Affairs (VA) analysis published in JAMA Ophthalmology , semaglutide use was associated with approximately double the risk of nonarteritic anterior ischemic optic neuropathy (NAION) compared with SGLT2 inhibitors in patients with type 2 diabetes. The study followed more than 102,000 patients for up to seven years, making it the most comprehensive assessment so far of this potential association

David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, et al

Idorn, K.W

Glucagon-like peptide1 receptor agonists and sodiumglucose cotransporter2 inhibitors as combination therapy for type 2 diabetes: a systematic review and metaanalysis

10.1007/s004419900093

Sin embargo, el tratamiento con semaglutide debe ser personalizado, considerando factores como los antecedentes familiares, la salud metablica y las preferencias personales