endocrinologist glp 1 GLP-1 medications have transformed the conversation around weight loss, but they're not the right choice for everyone., Stanford Medicine Sun Kim, MD, MS, and bariatric and minimally GLP-1 in Type 1 Diabetes:

F.Pi-SunyerX.DalyA.Wylie-RosettJ.KulkarniK.et al

A 52semanas se observa reduccin del volumen circulante y de la presin arterial, en relacin con la reduccin de adipoquinas y aldosterona, acompaado de disminucin de albuminuria y aumento de filtrado glomerular respecto a placebo, sugiriendo beneficio renal aadido47

In addition to these widely used AOMs, Exenatide, one of the earliest GLP-1 RAs approved by the FDA and EMA for T2DM management, is not indicated for weight management but remains clinically relevant, particularly in older adults with comorbid obesity and T2DM, given its long-term clinical experience and established tolerability profile [26,27,28]

GLP-1 can concurrently stimulate local inhibitory GABA neurons, which indirectly suppress neurons via agouti-related peptide/neuropeptide Y (AgRP + /NPY + ) signalling, thereby reducing feelings of hunger

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