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Patients with hepatic impairment : No dosage adjustment is required

No cases meeting Hy's Law criteria (ALT/AST elevation greater than 3 times ULN combined with bilirubin elevation greater than 2 times ULN) have been reported

It is contraindicated in patients with uncontrolled hypertension, seizure disorder, current or prior anorexia/bulimia, and those taking monoamine oxidase inhibitors
