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Description
But this enhancement in insulin secretion does not necessarily mean preservation of -cell function on a long-term basis

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Not suitable for pregnant or breastfeeding women, nor for individuals under 18 years of age

Unlike amphetamines, which increase multiple monoamines like dopamine and norepinephrine, fenfluramine exhibits greater selectivity in increasing 5-HT and has shown lower addictive potential [109, 110]

Additionally, incretin therapies can have overbearing negative side effects including hypoglycaemia (often in combination with other glucose-lowering treatments), nausea, vomiting, gastrointestinal upset (including diarrhoea) and injection site reactions that contribute to therapy discontinuation (Trujillo et al., 2021)

So when performing an IPGTT after 30 min of the dosing, the native peptide 1 was already inactive while hybrid 14 demonstrated full activity as predicted again from the blood glucose study
