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Recent developments underscore the relevance of GLP-1R agonists in addressing the complex interplay of cardiovascular-kidney-metabolic (CKM) syndrome, microvascular dysfunction, and metabolic-associated steatohepatitis (MASH)

Researchers pooled data on antihypertensive and lipid-lowering medication use from the STEP 1, 2, 3, 6 and 8 trials in a post hoc analysis published in Obesity

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As a result, dozens of upstream and downstream neural targets of 5-HT have been identified, revealing a multitude of neural circuits involved in mediating the anorexigenic effect of 5-HT

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